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In rare cases, congestive heart failure was noticed to be associated with Adalat, usually in patients already on a beta-blocker: propranolol (Inderal), metoprolol (Lopressor), etc. Hypotension on treatment by Adalat can occur, especially in patients already taking another blood pressure-lowering drug. Nifedipine decreases the elimination of digoxin (Lanoxin) by the kidneys which increases digoxin toxicity.

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